Free radical generation in germinal matrix hemorrhage
نویسندگان
چکیده
منابع مشابه
Germinal matrix hemorrhage-intraventricular hemorrhage: pathogenesis and outcomes
Germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) is one of the CNS injuries affecting preterm infants occurring in about 15%–20% of subjects weighing less than 1500 g. Currently, using ultrasonography, we recognize three grades of GMH-IVH. Grade I involving the subependymal parenchyma and/or extending in less than 10% of the ventricle, grade II with intraventricular bleeding not...
متن کاملRisk Factors of Germinal Matrix Intraventricular Hemorrhage in Premature Infants
OBJECTIVE To determine whether some clinical parameters can be used to predict the hemorrhage and whether the relationship between these clinical variables and the grades of hemorrhage is linear. METHODS A total of 230 premature infants, born at a gestational age less than 34 weeks were retrospectively reviewed. Germinal matrix-intraventricular hemorrhage (GM-IVH), the grade of the hemorrhage...
متن کاملPreventing Germinal Matrix Layer Rupture and Intraventricular Hemorrhage
The etiology of intraventricular hemorrhage (IVH) in extremely low birth weight preterm infants is multifactorial with circulatory instability and hemostasis being preeminent. This study sought to determine if the germinal matrix layer remained intact when platelets were above 200 × 10(9)/L, a near normal level, and fell below that when IVH occurred. This was a retrospective study of platelets ...
متن کاملImpaired Neurodevelopmental Outcome After Mild Germinal Matrix-Intraventricular Hemorrhage.
Germinal matrix–intraventricular hemorrhage (GMH-IVH) is a common and characteristic form of intracranial hemorrhage occurring in the premature infant. The hemorrhage originates in small blood vessels in the subependymal germinal matrix (also termed the ganglionic eminence) and may disrupt the ependymal lining and extend into the lateral ventricle. Severe IVH consists of large amounts of intrav...
متن کاملHuman germinal matrix: venous origin of hemorrhage and vascular characteristics.
PURPOSE To examine the vascular supply and architecture of the germinal matrix in the preterm neonatal brain and to determine whether veins or arterioles are the source of germinal matrix hemorrhage. METHODS Brains from eight preterm neonates (24 to 35 weeks' gestation) and two full-term infants were fixed in alcohol, embedded in celloidin, sectioned at 100- and 500-micron thicknesses, staine...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2008
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.22.1_supplement.732.10